I am sort of surprised you didn't mention some of the possible social and psychological ramifications.
As humans we communicate to form relationships, give guidance, respond and take action with compassion, have a positive influence on the actions of others, whether on a interpersonal and social or political level, to mention just a few aspects of our interpersonal communication.
The fact that no computer Chat algorithm can do that, but maybe provide some semblance of interaction, can have may negative ramifications, beyond the positive one of providing information as say, google does.